Effect of Corona 19 on the kidneys
Corona19 virus has been shown to affect mainly the lungs, but it also affects the kidneys. This was confirmed in some of the first studies conducted in China.
Recently, the scientific community is looking into the effects of Corona 19 on the kidneys. Experts are discovering new symptoms and new complications from Corona19 every day. The question emerged during the hospitalization when a patient developed a problem known as acute kidney injury.
Although there is currently no clear mechanism, kidney specialists agree that SARS-CoV-2 is responsible for some level of kidney damage that varies with frequency. In some regions, cases of less than 1% of cases of acute kidney injury have been reported, while in other countries, up to 30% of cases are reported.
Patients with kidney damage due to corona19 have the worst prognosis. Acute kidney damage is difficult to treat in intensive care facilities.
Scientific study of corona19's effects on the kidneys
In the early days of the development of coronavirus in China, there was a journal warning of kidney damage caused by SARS-CoV-2. Some were based on a study of a small number of patients, while others were able to include nearly 1,000 patients.
One of the early publications investigated the incidence of acute renal failure in coronavirus patients. Acute renal failure is that the kidneys are unable to perform the filtering function.
Up to 9% of patients in this study experienced kidney failure. This means the appearance of proteinuria or the loss of protein through urine. In addition, the level of a substance called creatine in the blood increases, and when it exceeds a certain amount, it turns into a toxin.
Patients with this problem underwent kidney tomography. The results of the imaging revealed that 100% of them experienced kidney changes. Mainly inflammation and accumulation of body fluids were found.
Another early scientific study on the effects of corona19 on kidneys was also done in China. In this study, researchers found kidney failure in 3% of hospitalized patients. At the same time, a 40% incidence of hematuria with blood present in the patient's urine was found.
Scientific research conducted in China warns of kidney damage associated with coronavirus infectious diseases.
Three factors in kidney damage caused by a coronavirus
There are three aspects we should consider the effects of corona19 on the kidneys. These factors may work alone or together and may differ from patient to patient. In some cases, damage caused by SARS-CoV-2 occurs directly, but indirectly as a result of treatment.The three elements are:
- The virus itself: Kidney specialists agree that the kidneys are one of the organs that are attacked by the disease along with the lungs. The respiratory and renal systems have common substances, including renin and angiotensin. These substances are linked by receptors, which may be proteins that SARS-CoV-2 utilizes as an entry port for human cells.
- Symptoms affecting the whole body: When severe forms of corona19 appear, many organs are affected by body failure. A similar situation occurs when pneumonia is caused by other causes, which can lead to kidney failure due to a series of effects.
- Treatment: Although there is no completely effective treatment protocol for coronavirus, scientists are investigating alternatives with a variety of medicines. Some of these alternatives are medicines that can cause side effects in the kidneys and, on their own, lead to kidney failure.
Coronavirus can enter kidney cells and cause damage, but the damage may be the result of medications and treatments.
How does Corona 19 affect your kidneys?
The theory of how SARS-CoV-2 penetrates the body is based on the scientists' knowledge of how coronavirus infects lung cells. We know that the key to coronavirus entry is the ACE2 protein.
Since the bed on the virus surface partially matches ACE2, the virus can enter the lung cells. ACE2 is a receptor that all humans have. It is also present in the kidney and is a protein involved in the regulation of arterial pressure.
The regulating system currently mentioned is the Lenin-Angiotensin System. This is one of the advantages of using drugs to treat arterial hypertension. For this reason, experts speculate that hypertensive patients have a higher mortality rate in Corona19 infectious diseases.
The kidneys also appeared to have similar proteins, considering taking part in the same Lenin-Angiotensin system. The hypothesis that corona19 can follow a similar pathway in kidney cells, as in lung cells, is being considered.
Kidney patients belong to the risk group
It is necessary to clearly point out that patients with kidney disease belong to the risk group with greater risk at the time of the corona19 pandemic spread. Therefore, it is necessary to exercise extreme caution and practice social isolation.It is also essential to continue medication. If symptoms require consultation with a physician, a complete medical history should be provided so that the physician can perform the most appropriate course of treatment in a particular case.
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